A colloidal gold platform is a diagnostic technology that uses gold nanoparticles to detect the presence of biomolecules or microorganisms in a patient sample. The technology relies on the principles of immunochromatography, where the sample is added to a device containing gold labels coated with antibodies or antigens. If the target biomolecule or microorganism is present, it will bind to the gold label, resulting in a visible change, such as a color change. Colloidal gold platforms are commonly used in rapid diagnostic tests for infectious diseases, such as HIV, malaria, and COVID-19. The technology is affordable, easy to use, and produces results quickly, making it a valuable diagnostic tool in resource-limited settings.
As a type of POCT platforms, the colloidal gold platform works by using gold nanoparticles that are coated with antibodies or antigens to detect the presence of specific biomolecules or microorganisms in a patient sample. If the target molecule is present, it binds to the gold label, resulting in a visible change such as a color change.
Compared to other POCT platforms, the colloidal gold platform stands out for its affordability, simplicity and ease of use. The technology provides quick results, making it ideal for use in resource-limited settings. Colloidal gold platforms can also be used for a variety of diagnostic applications.
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